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【Animal Modeling】-Study on the alleviation of exercise via FoxO1-lipophagy pathway. Study on hyperlipidemia in ApoE-/- mice

【Animal Modeling】-Study on the alleviation of exercise via FoxO1-lipophagy pathway. Study on hyperlipidemia in ApoE-/- mice

Lipophagy is a selective autophagy targeting adipose and is regulated by FoxO1. As an effective means of regulating lipid metabolism disorders, there is no report on whether exercise is related to FoxO1-lipophagy process in hyperlipidemia. In this st...

2023-07-12
【Animal modeling】-Polymorphism analysis of PPARγ2 gene promoter in Wuzhishan miniature pigs

【Animal modeling】-Polymorphism analysis of PPARγ2 gene promoter in Wuzhishan miniature pigs

To analyze the polymorphisms in the regulatory region of the PPARγ2 gene promoter in Wuzhishan miniature pigs...

2023-07-12
【Animal modeling】-Effect of simvastatin combined with risedronate on dexamethasone-induced bone loss in rats

【Animal modeling】-Effect of simvastatin combined with risedronate on dexamethasone-induced bone loss in rats

To analyze the effects of simvastatin and risedronate sodium alone and in combination on dexamethasone-induced osteoporosis in rats...

2023-07-12
【Animal Modeling】-Papaverine for asthma and ulcerative colitis model

【Animal Modeling】-Papaverine for asthma and ulcerative colitis model

To explore the molecular significance of papaverine on the regulation of Chinese herbal medicine regression theory on the respiratory tract and inflammatory bowel disease. Analyze the changes of differentially expressed genes in the two animal models...

2023-07-12
[Animal modeling] - Protective effect of hemorrhoids magnetized ointment on hemorrhoids model in mice

[Animal modeling] - Protective effect of hemorrhoids magnetized ointment on hemorrhoids model in mice

To study the protective effect of hemorrhoids magnetized ointment on hemorrhoids induced by acetic acid in mice...

2023-07-10
【Animal Modeling】-High-fat diet-induced non-alcoholic fatty liver disease cynomolgus monkey model

【Animal Modeling】-High-fat diet-induced non-alcoholic fatty liver disease cynomolgus monkey model

To establish an animal model of high-fat diet-induced non-alcoholic fatty liver disease in cynomolgus monkeys, analyze the effect of high-fat diet feeding time on the formation of NAFLD in animals, and explore the relationship between high-fat diet f...

2023-07-07
【Animal Modeling】-A weekly subcutaneous injection of rhPTH(1-34) promotes fracture healing in rats

【Animal Modeling】-A weekly subcutaneous injection of rhPTH(1-34) promotes fracture healing in rats

To observe the effect of weekly subcutaneous injection of parathyroid hormone rhPTH (1-34) on fracture healing in rats...

2023-07-04
【Animal modeling】-Comparative study on blood physiological and biochemical indexes of normal Bama miniature pigs and F5 generation of hyperglycemic families

【Animal modeling】-Comparative study on blood physiological and biochemical indexes of normal Bama miniature pigs and F5 generation of hyperglycemic families

To compare and analyze the blood physiological and biochemical indicators of normal Bama miniature pigs and F5 individuals of hyperglycemic families...

2023-07-04
Polymorphisms of SLA Class II Gene in SPF Large White and Landrace Pigs for Research

Polymorphisms of SLA Class II Gene in SPF Large White and Landrace Pigs for Research

To study the polymorphism of SLA class II gene in SPF large white and landrace pigs...

2023-07-04
【Animal Modeling】-Evaluation of the Operational Effect of Animal Nasal Aerosol Exposure Device

【Animal Modeling】-Evaluation of the Operational Effect of Animal Nasal Aerosol Exposure Device

The purpose of this study is to investigate whether the animal nasal aerosol exposure device can operate normally and generate aerosol particles of a certain size, and to explore the air tightness, distribution uniformity and disinfection of the syst...

2023-07-04
【Animal modeling】-Effect of simvastatin combined with risedronate on dexamethasone-induced bone loss in rats

【Animal modeling】-Effect of simvastatin combined with risedronate on dexamethasone-induced bone loss in rats

To analyze the effects of simvastatin and risedronate sodium alone and in combination on dexamethasone-induced osteoporosis in rats...

2023-07-04
【Animal Modeling】-Induced bladder cancer animal model

【Animal Modeling】-Induced bladder cancer animal model

There are two ideal animal carcinogenic chemicals: N-butyl-N-(4-hydroxybutane 1). -Nitrosamines, BBN) and N*methyl-N-nitrosourea (N-methyl-N-nitrosourea, MNU) are representative nitroso compounds and N-[4-(5 -Nitro-2-furyl)-2, -thiazolyl]carboxamide...

2023-07-03
【Animal Modeling】-Establishment of a mouse model of chronic thrombus induced by carrageenan

【Animal Modeling】-Establishment of a mouse model of chronic thrombus induced by carrageenan

To screen the conditions of chronic thrombosis mouse model by treating mice with different concentrations of carrageenan solution by continuous intraperitoneal injection...

2023-07-03
【Animal Modeling】-Effects of high-fat diet and K/BxN serum on the immune system of ApoE knockout mice

【Animal Modeling】-Effects of high-fat diet and K/BxN serum on the immune system of ApoE knockout mice

To examine the effects of high-fat diet and K/BxN serum on the distribution of immune cells in ApoE knockout (ApoE-/-) mice...

2023-06-30
【Animal modeling】-Effect of paeoniflorin on intracellular Ca2+ in rat dorsal root neurons

【Animal modeling】-Effect of paeoniflorin on intracellular Ca2+ in rat dorsal root neurons

To establish a method to evaluate the effect of paeoniflorin on the concentration of free Ca2+ in rat dorsal root ganglion neurons...

2023-06-30
【Animal modeling】-The expression characteristics of CD32 in rhesus monkey model of latent HIV infection

【Animal modeling】-The expression characteristics of CD32 in rhesus monkey model of latent HIV infection

To establish a rhesus monkey model of latent infection with SIVmac239, to study the expression characteristics of CD32 in resting, activated and/or memory CD4+ T cell subsets, and to analyze its potential as a marker of AIDS latent reservoir...

2023-06-29