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【Animal Modeling】-Analysis of Transcriptional Levels of CMAH Gene in Different Tissues of Mice

【Animal Modeling】-Analysis of Transcriptional Levels of CMAH Gene in Different Tissues of Mice

The sialic acid and its derivatives contained in mammalian cells mainly include N-acetylneuraminic acid, N-glycolylneuraminic acid and deaminated neuraminic acid. The synthesis of Neu5Gc under the catalysis of acid hydroxylase? In this study, the rel...

2023-05-25
【Animal Modeling】-Fluorescence two-dimensional electrophoresis to detect the differences in liver tissue proteomics between male and female mice

【Animal Modeling】-Fluorescence two-dimensional electrophoresis to detect the differences in liver tissue proteomics between male and female mice

To detect the differences in the expression of proteomes in the liver tissue of male and female mice, and to explore the mechanism of gender differences in the occurrence of liver diseases...

2023-05-25
【Animal Modeling】-Establishment and Application of In Vitro Culture System of Mouse Small Intestinal Organoids

【Animal Modeling】-Establishment and Application of In Vitro Culture System of Mouse Small Intestinal Organoids

To establish an in vitro model of intestinal epithelial cells—small intestinal organoid culture system, and to explore its related pathological detection techniques, so as to provide a convenient platform for the in vitro research of intestinal-relat...

2023-05-25
【Animal modeling】-Prokaryotic expression of monkey D-type retrovirus p27 gene and establishment of flow immunofluorescence microsphere detection technology

【Animal modeling】-Prokaryotic expression of monkey D-type retrovirus p27 gene and establishment of flow immunofluorescence microsphere detection technology

To construct the p27 protein of simian D-type retrovirus, and establish a flow immunofluorescence microsphere detection technology for the detection of simian D-type retrovirus...

2023-05-25
【Animal Modeling】-The mechanism of acute hyperglycemia affecting the first phase insulin secretion in mice

【Animal Modeling】-The mechanism of acute hyperglycemia affecting the first phase insulin secretion in mice

To observe the function and morphological changes of acute hyperglycemia affecting the first phase insulin secretion in mice...

2023-05-24
[Animal Modeling]-Rat models of fluorosis of different sexes

[Animal Modeling]-Rat models of fluorosis of different sexes

Do you want to establish an animal model of male and female fluorosis rats to study the gender differences in fluorosis?...

2023-05-24
[Animal Modeling]-Explore the effect of natural hot spring water on lipid peroxidation in aged mice

[Animal Modeling]-Explore the effect of natural hot spring water on lipid peroxidation in aged mice

To study the effectiveness and feasibility of vaccine immune intervention with human-derived RBP-4 as the target of insulin resistance, and to provide basic research data for advancing the development of new therapies for type 2 diabetes...

2023-05-24
[Animal Modeling]-The combined effect of estrogen and androgen on the blood lipid level and coagulation function of hyperlipidemia mice

[Animal Modeling]-The combined effect of estrogen and androgen on the blood lipid level and coagulation function of hyperlipidemia mice

To explore the effect of combined action of estrogen and androgen on blood lipid level and coagulation function in hyperlipidemia mice...

2023-05-23
【Animal Modeling】-Von Willebrand Disease Mini Pig Model

【Animal Modeling】-Von Willebrand Disease Mini Pig Model

A research team led by Zhou Qi, a researcher at the Institute of Zoology, Chinese Academy of Sciences, obtained vWF knockout pigs for the first time using CRISPR/Cas9 technology and established a miniature pig model of von Willebrand disease...

2023-05-23
【Animal Modeling】-Establishment and evaluation of rabbit knee osteoarthritis model

【Animal Modeling】-Establishment and evaluation of rabbit knee osteoarthritis model

Preparation and evaluation of rabbit knee osteoarthritis model by rabbit cartilage defect...

2023-05-22
【Animal modeling】-Effects of bis(2-ethylhexyl) phthalate exposure during pregnancy on growth and development of mouse placenta

【Animal modeling】-Effects of bis(2-ethylhexyl) phthalate exposure during pregnancy on growth and development of mouse placenta

Through exposure to bis(2-ethylhexyl) phthalate (DEHP) during pregnancy, observe the effects of DEHP exposure on the growth and development of mouse placenta, the number of uNK cells at the maternal-fetal interface, and angiogenesis in vivo...

2023-05-22
[Animal modeling]-Staphylococcus aureus endophthalmitis animal model

[Animal modeling]-Staphylococcus aureus endophthalmitis animal model

Replication method Cultivation of Staphylococcus aureus ATCC29213 strain and mix with physiological saline to prepare a bacterial suspension of 10000CFU/ml...

2023-05-19
Establish a model of heart failure induced by high-fat diet in fruit flies

Establish a model of heart failure induced by high-fat diet in fruit flies

Establish a model of heart failure induced by high-fat diet in fruit flies...

2023-05-17
【Animal Modeling】-Effects of Electroacupuncture on Synaptic Plasticity and Microglia Polarization in Rats with Cerebral Ischemia

【Animal Modeling】-Effects of Electroacupuncture on Synaptic Plasticity and Microglia Polarization in Rats with Cerebral Ischemia

Explore the electroacupuncture synaptic plasticity and microglia polarization in rats with focal cerebral ischemia, and detect the expression of miR-21/signal transducer and activator of transcription 3 (STAT3) pathway...

2023-05-17
【Animal Modeling】-Precocious puberty rat model of stagnation of phlegm and dampness

【Animal Modeling】-Precocious puberty rat model of stagnation of phlegm and dampness

  Explore a systematic evaluation method for the model of blood stasis syndrome in rats with precocious puberty...

2023-05-17
【Animal modeling】-Application of optical fiber-guided tracheal intubation in rodents

【Animal modeling】-Application of optical fiber-guided tracheal intubation in rodents

To establish a simple method for endotracheal intubation in rodents, and to establish various animal models that require endotracheal intubation...

2023-05-16