【Animal modeling - Drug efficacy evaluation】 - Repeated immunization induced ulcerative colitis in rats

Wistar rats, female, weighing (180 ± 10) g; Medications: pentobarbital, penicillin; Equipment: body locator, electronic stimulator...

2024-08-06

[Animal Modeling Drug Efficacy Evaluation] - Staphylococcus aureus Endometritis Animal Model

Cultivate Staphylococcus aureus ATCC29213 strain and prepare a bacterial suspension of 10000 CFU/ml using physiological saline...

2024-08-06

[Animal modeling - Drug efficacy evaluation]- Establishment of post-traumatic epilepsy animal model by iontophoresis method

Animal: Wistar rats, male, weighing 200-250g; Medication: pentobarbital, FeCl3 solution; Instruments: rat stereotaxic apparatus, wireless Bluetooth EEG monitoring system, high-speed dental drill, tooth holder powder, 1 PVC thin tube with an inner dia...

2024-08-06

[Animal Modeling Drug Efficacy Evaluation] - Rat Pseudomonas aeruginosa Pneumonia Model

Secretory Pseudomonas aeruginosa PAO1 strain and its variant PAOR strain were cultured overnight in tryptone soy broth at 37 ° C. After centrifugation, they were suspended in PBS (pH 7.4), washed by centrifugation, and the precipitate was suspended i...

2024-08-06

[[Animal modeling - efficacy evaluation] - primary diabetes BB rats

BB Wistar rat is a spontaneous diabetes animal model...

2024-08-06

[Animal Modeling - Efficacy Evaluation] - Mongolian Sand Rat Helicobacter pylori Model

5-week-old male Mongolian sand rats without specific pathogen grade were fed standard feed and sterilized water with libitum...

2024-08-06

[Animal Modeling - Pharmacological Evaluation] - Penicillin induced Epilepsy Animal Model

SD rats, half male and half female, weighing (300 ± 20) g; Drug: Penicillin...

2024-08-06

[Animal Modeling Drug Efficacy Evaluation] - Rabbit Pseudomonas aeruginosa Pneumonia Model

Select a small amount of mucinous PA colonies stored at 4 ℃, incubate them in MH broth at 37 ℃ for 24 hours, and prepare a bacterial suspension of 0.5 units using MH broth. Freshly prepare on the same day of use. New Zealand rabbits aged from 18 to 2...

2024-08-06

【Animal modeling - Drug efficacy evaluation】 - Cortical injection of ferrous chloride to establish a traumatic epilepsy animal model

Healthy adult male SD rats weighing 180-220g; Drug: 10% chloral hydrate, FeCl2 solution...

2024-08-06

[Animal Modeling Drug Efficacy Evaluation] - Rhesus Monkey HGV Infection Model

Experimental rhesus monkeys weighing 2.5-6.5kg and aged 2-8 years were selected. Prior to infection, ALT enzyme activity was detected to be normal, and liver biopsy showed no dynamic liver pathological changes...

2024-08-05

[Animal Modeling - Pharmacological Evaluation] - Model of Memory Consolidation Disorder Caused by Electric Shock

Wistar rats, weighing (216 ± 10) g; Instrument: Electroconvulsive device...

2024-08-05

[Animal Modeling - Pharmacological Evaluation] - Model of Memory Consolidation Disorder Caused by Brain Hypoxia

mouse; Drug: a mixture of 96.2% N2 and 3.8% O2 gas, pure CO2, NaNO2; Instrument: a sealed jar...

2024-08-05

[Animal Modeling - Efficacy Evaluation] - Foot and Mouth Disease Virus Animal Model

Dilute the foot-and-mouth disease virus ORMF8 with 0.01mol/L PBS (pH 7.4) to an LD50 of 10-3 to 10-7/0.2ml, and then inject each titer of virus solution intradermally through the hind limb toes of guinea pigs, with an injection dose of 0.2ml per anim...

2024-08-05

【Animal Modeling - Pharmacological Evaluation】 - Tree Shrew Hepatitis B Model

Tree shrews were inoculated via femoral vein with 0.5ml of serum from hepatitis B patients with positive hepatitis B B virus surface antigen (HBsAg) and hepatitis B B virus e antigen (HBeAg)...

2024-08-05

[Animal modeling - Drug efficacy evaluation] - Pulmonary heart disease

Select adult Japanese large eared rabbits and inject a 1% mass fraction of ferric chloride aqueous solution into the rabbit ear vein. Inject 0.5ml twice a week from week 1 to week 4; From the 5th to the 6th week, twice a week, 0.75ml each time; In th...

2024-08-05

[Animal Modeling - Pharmacological Evaluation]- Depression Models in Solitary or Separate Care

Some primates or non primates may exhibit characteristic symptoms such as agitation, sleep disorders, and lamenting after separation from their offspring...

2024-08-05