Animal experiments: blood pressure drugs are expected to treat Parkinson\'s disease and dementia

Prescription drugs for the treatment of hypertension have shown promise for diseases such as Parkinson\'s disease, Huntington\'s disease and dementia in studies conducted on mice and zebrafish at the University of Cambridge...

2020-11-23

To investigate the neurotoxic effects of flame retardant TCPP (tris(2￣chloroisopropyl) phosphate) exposure on mice and the study of related mechanisms

To investigate the neurotoxic effects of flame retardant TCPP (tris(2￣chloroisopropyl) phosphate) exposure on mice and the study of related mechanisms...

2020-11-23

Effect of Astragalus on Endoplasmic Reticulum Stress Response in Vascular Remodeling in Hypertensive Rats

To study the effect of Astragalus on the endoplasmic reticulum stress response (ERS) in vascular remodeling in hypertensive rats, and to explore the molecular mechanism of its vascular protection...

2020-11-21

Effect of Perfluorooctane Sulfonate on Rat Embryo Development and Placental IGF-1 Expression

To explore the effects of different doses of perfluorooctane sulphonate (PFOS) on rat embryo development and the expression of insulin-like growth factor IGF-1 (insulin-like growth factor-1) in the placenta...

2020-11-21

Study on the mechanism of Shenyi capsule combined with 5-fluorouracil on angiogenesis of colon cancer in mice

To investigate the inhibitory effect of Shenyi capsule combined with 5-fluorouracil (5-fluorouracil, 5-FU) on colon cancer growth and angiogenesis and its possible mechanism...

2020-11-21

Study on the mechanism of aspirin on controlling salt-sensitive hypertension in rats

To explore the regulating effect and related mechanism of aspirin on salt-sensitive hypertension in rats...

2020-11-21

Effects of Maca Combined with Exercise Therapy on Respiratory Chain Enzyme Activity of Mitochondria and Renal Function in Diabetic Rats

To observe the effect of maca combined with exercise therapy on the activity of renal mitochondrial respiratory enzymes and renal function in diabetic rats...

2020-11-21

Effects of repeated propofol anesthesia on spatial memory and long-term enhancement of young rats under hypoxic conditions

Propofol is the most commonly used intravenous induction and maintenance anesthesia. Hypoxemia is a common complication during anesthesia...

2020-11-21

Efficacy and safety of new naltrexone in the treatment of type 1 diabetic dry eye

Tear deficiency dry eye disease (TDDE) or aqueous dry eye disease (DED) refers to abnormal tear secretion related to pathophysiology and/or environmental factors...

2020-11-21

Recoding human islet cells may relieve diabetes in mice

A paper reported that human alpha and gamma islet cells can be recoded to produce insulin. Usually, only pancreatic beta cells can produce insulin...

2020-11-21

The protective effect of bifidobacteria on liver function in rats with chronic alcoholic liver injury

To explore the protective or influence effect of Bifidobacterium (BIFI) on the liver function of chronic alcoholic liver injury (CALI) rats, and preliminarily explore its mechanism...

2020-11-21

Abnormal glucose metabolism leads to weight change in acute phase of SIVmac239 infection in Beiping-top monkey

To explore the effects of inflammatory factors, lipid metabolism and glucose metabolism on body weight in the acute phase of AIDS...

2020-11-21

Effects of N-acetylcysteine on oxidative stress and FoxO1 activity in the liver of type 2 diabetic rats

To explore the effect of antioxidant N-acetylcysteine (NAC) on liver oxidative stress and FoxO1 activity in type 2 diabetic rats...

2020-11-21

Effect of Xingnao Zaizao Capsule on Formaldehyde-induced Memory Impairment in Mice

To explore the effect of Xingnao Zaizao Capsule on memory impairment in mice induced by formaldehyde and its mechanism...

2020-11-21

Effects of curcumin pretreatment on renal pathological damage and oxidative stress in rats with different degrees of heatstroke in dry-heat environment

To observe the effect of curcumin pretreatment on renal pathological changes and oxidative stress 9 levels in renal tissues of rats with different degrees of heat stroke...

2020-11-21

Effect of emodin on fat browning in ApoE knockout mice

Observe the effect of emodin on fat browning in apolipoprotein E knockout (ApoE-/ -) mice, and explore its mechanism of improving blood stasis such as hyperlipidemia...

2020-11-21