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Research reveals the underlying cause of multiple sclerosis

Research reveals the underlying cause of multiple sclerosis

An international research team led by the University of British Columbia has made a scientific progress that they hope will lead to the development of preventive treatments for multiple sclerosis (MS)...

2020-10-26
Study established a new mouse model of psoriatic arthritis

Study established a new mouse model of psoriatic arthritis

Psoriatic arthritis (PsA) is a chronic inflammatory disease that reduces the patient’s mobility and flexibility...

2020-10-26
Establishment and evaluation of rabbit knee osteoarthritis model

Establishment and evaluation of rabbit knee osteoarthritis model

The animals were randomly divided into 3 groups according to body weight and gender: sham operation group, model group and positive control glucosamine group, each with 12 animals...

2020-10-26
Scientists identify compounds that stimulate muscle cells in mice

Scientists identify compounds that stimulate muscle cells in mice

Researchers at the University of California, Los Angeles have identified a compound that can replicate the effects of exercise in the muscle cells of mice...

2020-10-26
Advantages of immunodeficiency mice BRGSF mice in gene therapy

Advantages of immunodeficiency mice BRGSF mice in gene therapy

Since 2017, the field of gene therapy has been in favor of policy, capital attention, and the scientific community is very optimistic. Whether it is a company that focuses on the research and development of one or several gene therapy products, or a ...

2020-10-26
Reversing type 1 diabetes, rare NEJM cases suggest JAK inhibitor potential

Reversing type 1 diabetes, rare NEJM cases suggest JAK inhibitor potential

We know that patients with type 1 diabetes suffer from absolute insulin deficiency due to islet β-cell damage. At present, insulin therapy is mainly used. Restoring β-cell function and reversing the pathological state is still a big challenge...

2020-10-23
What is the mechanism of Peli1\'s regulation of microglia phagocytosis and Alzheimer\'s pathology?

What is the mechanism of Peli1\'s regulation of microglia phagocytosis and Alzheimer\'s pathology?

E3 ubiquitin ligase (ie Peli1) directly mediates C/EBPβ ubiquitination modification and induces its degradation, a new mechanism that affects the phagocytic function of amyloid β (Amyloid-β, Aβ) by microglia. The pathological mechanism and clinical t...

2020-10-23
Type 1 diabetes may start in the womb as early as possible?

Type 1 diabetes may start in the womb as early as possible?

Diabetes diagnosed within 6 months of age is usually considered to be caused by a single gene mutation, not type 1 diabetes...

2020-10-23
Respiratory syncytial virus (RSV) vaccine quickly induces strong immunity!

Respiratory syncytial virus (RSV) vaccine quickly induces strong immunity!

GlaxoSmithKline (GSK) recently announced that its respiratory syncytial virus (RSV) candidate vaccine is well tolerated and immune to maternal immunity (GSK3888550A vaccine) and elderly immunity (GSK3844766A vaccine) in Phase I/II studies. Strong ori...

2020-10-23
The new generation of PI3Kδ inhibitor/new CD20 monoclonal antibody combination is more effective in the treatment of leukemia

The new generation of PI3Kδ inhibitor/new CD20 monoclonal antibody combination is more effective in the treatment of leukemia

The U.S. Food and Drug Administration (FDA) granted Fast Track Qualification (FTD) for the combined use of ubrituximab and umbralisib (U2) to treat adult chronic lymphocytic leukemia (CLL)...

2020-10-23
Key brain mutations affect obesity

Key brain mutations affect obesity

Scientists at the University of Copenhagen have found that obesity is a brain-related disease. Specifically, because genetic mutations affect the way the brain processes sensory information and regulates diet and behavior, some people are at increase...

2020-10-23
What are the risks of breast cancer drugs?

What are the risks of breast cancer drugs?

New research led by Flinders University has found a link between beta-blockers and the survival outcomes of certain breast cancer patients...

2020-10-23
Research reveals the vulnerability of cancer cells

Research reveals the vulnerability of cancer cells

One of the biggest challenges in developing cancer drugs is the diversity of cancer types. Cancers originate from a variety of cells and tissues. Each cancer has its own characteristics, performance and sensitivity to anticancer drugs....

2020-10-23
COVID-19 rapid test shows high sensitivity

COVID-19 rapid test shows high sensitivity

Researchers from the University of Sheffield recently published their evaluation results of a new, rapid COVID-19 testing technology...

2020-10-23
Spinal cord stem cells can help repair after injury

Spinal cord stem cells can help repair after injury

Spinal cord injury usually leads to permanent dysfunction. A new study published in the \\\"Science\\\" magazine of the Karolinska Institute in Sweden shows that it can stimulate mouse spinal cord stem cells to form a large number of new ol...

2020-10-23
Oral microorganisms cause cancer

Oral microorganisms cause cancer

A study by Yvonne Kapila of the University of California, San Francisco and others published in the journal PLOS Pathogen on October 1 showed that pathogens found in the tissues around the teeth can lead to the occurrence of highly aggressive oral ca...

2020-10-23