【Animal Modeling】-TALEN Construction of Fndc5 Gene Knockout Mice and Preliminary Analysis

To provide an animal model for subsequent research by constructing Fndc5 knockout mice...

2023-12-07

[Animal modeling] - Establishment and study of hyperuricemia model in rats

To establish a rat model of hyperuricemia and investigate whether hyperuricemia can cause secondary cardiovascular diseases...

2023-12-07

[Animal modeling] Detection of salsolinol N-methyltransferase activity in 6-hydroxydopa model rats

To establish a rat model of Parkinson\\\'s disease (PD) with 6-hydroxydopamine (6-OHDA) and determine the activity of salsolinol N-methyltransferase (SNMT) in peripheral blood lymphocytes of rats...

2023-12-06

[Animal modeling] - Establishment of a mouse model of IgA nephropathy induced by superantigen staphylococcal enterotoxin B

To establish a mouse model of IgA nephropathy and observe the biochemical and pathological characteristics of the model...

2023-12-06

[Animal modeling] Expression mode of TETs protein in urethane induced lung cancer model of mice

To investigate the expression pattern of TET family proteins in mouse lung cancer model...

2023-12-06

[Animal modeling] - Establishment and evaluation of a mouse model of acute lung injury induced by cholic acid

To establish a mouse model of acute lung injury induced by cholic acid, screen the drug delivery mode, and explore the feasibility of lung injury induced by cholic acid...

2023-12-06

【Animal modeling】-Effect of different intervention programs of simvastatin on bone mass in osteoporotic rats

To explore and compare the intervention effects of simvastatin on bone loss and bone quality decline in ovariectomized rats under different intervention programs...

2023-12-06

[Animal modeling] - Urine metabolomic study on the rat model of abnormal black bile syndrome in Uygur medicine

To evaluate and discuss the biological markers of the rat model of abnormal black bile syndrome in Uyghur medicine by combining the observation of external characteristics with the study of urine metabolome...

2023-12-06

【Animal Modeling】-Comparison and Behavioral Evaluation of Rat Spinal Cord Contusion Models

To establish spinal cord injury models in rats with different degrees of MASCIS and IH, and to study the relationship between injury degree, modeling method, behavior, and anatomical results...

2023-12-06

[Animal modeling] - Establishment of rat lumbar ventral nerve root traction model

In order to study the pathogenesis of amyotrophic lateral sclerosis and drug development, the rat model of ventral nerve root traction of the fourth lumbar spine was established, and the validity of the model was verified with brain-derived neurotrop...

2023-12-04

[Animal modeling] - Experimental study on the rat model of hypertension combined with hyperlipidemia

To establish a model of spontaneously hypertensive rats (SHR) with hyperlipidemia by feeding them with high-fat diet, and to evaluate their heart and kidney injuries, so as to provide pharmacodynamic animal models and relevant methods for the evaluat...

2023-12-04

【Animal modeling】-Intervention effect of chitosan on PM2.5-induced acute lung injury in mice

To investigate the intervention effect of chitosan on PM2.5-induced acute lung injury in mice...

2023-12-04

【Animal modeling】-Construct a rat COPD-OSAHS overlap syndrome model by smoking and intermittent hypoxia

To construct a rat model of COPD-OSAHS overlap syndrome, and to provide a feasible means and experimental platform for basic research on OS...

2023-12-04

[Animal modeling] Establishment of cough variant asthma model in Brown Norway rats

To establish a simple and practical animal model of cough variant asthma in Brown\\\'s Norway (BN) rats sensitized with ovalbumin (OVA)...

2023-12-04

[Animal modeling] - Study on coagulation function of rat sepsis model

To investigate the changes of coagulation function in sepsis rat model induced by cecal ligation and puncture...

2023-12-04

[Animal modeling] - Establishment and evaluation of a mouse model of endogenous infection induced by intestinal dissemination

To establish a mouse model of endogenous infection induced by intestinal dissemination, so as to provide a reliable experimental model for studying the mechanism of intestinal microecology and endogenous infection...

2023-12-04