![[Animal Modeling] - Animal Model of Hypertensive Liver Yang Hyperactivity Syndrome with Shuangshen Shuangjia and Guanfuzi Tang](/./uploads/images/default/default.png)
Adult rats were anesthetized, and a longitudinal incision was made in the middle of the abdomen. The bilateral renal arteries were bluntly separated. Silver clips with an inner diameter of 0.2-0.23mm were used to clamp the initial part of the bilater...
2023-09-13
After fasting for 18 hours and water deprivation for 1 hour, rats were gavaged with 0.1% indomethacin 5ml/kg. The control group was given an equal amount of physiological saline...
2023-09-13
Animal models related to the Stat3 pathway: Sano S et al. continuously activated the Star3 pathway by inserting the KRT5 promoter into basal keratinocytes, leading to spontaneous or psoriatic skin lesions in response to external damage, such as kerat...
2023-09-13
Model rats were anesthetized by intraperitoneal injection of pentobarbital at a dose of 30mg/kg, followed by skin disinfection with iodine. After laparotomy, the stomach and upper jejunum were exposed, and the anterior stomach was fixed together with...
2023-09-13
Application of propranolol to create a guinea pig ear psoriasis model. This model is commonly used in China. Huang et al. applied 5% propranolol to the ears of guinea pigs (350-400g) (0.3g of drug per cm2) twice a day for 2 weeks, while using 1% dini...
2023-09-13
Animal modeling materials: Adult rats, male and female, weighing 200-250g; Drugs: 2,4-dinitrochlorobenzene, acetone, acetic acid, ethanol; Instrument: 3mm diameter nylon catheter...
2023-09-12
Reproduction method: Adult rats were gavaged with 4 ℃ vinegar daily, with a volume of 10ml/kg body weight for 10 consecutive days. During this period, observe changes in animal appearance and behavior, weight, food intake, and water intake. On the da...
2023-09-12
Reproduction method: Adult rats were raised in a single cage and subjected to external abdominal irradiation at a dose of 250 rad/min. The first dose was followed by a second dose of enhancement 7 days after the first dose. The changes in food intake...
2023-09-12
Toll like receptor 2 gene knockout mice. In Toll like receptor 2 gene knockout mice, homozygotes can survive with normal appearance and behavior. Macrophages from mouse bone marrow cannot stimulate immune responses to lipoproteins of Borrelia burgdor...
2023-09-12
Reproduction method: Adult rats were raised in a single cage, and the experimental rat cage was fixed to the oscillator using a tray. The oscillator was controlled by a relay to stop for 10 minutes every 20 minutes of vibration, with an average of 10...
2023-09-12![[Animal modeling] - T cell deficient mice](/./uploads/images/default/default.png)
The homozygous CD4 antigen knockout mice cannot express CD4 on the cell surface. CD8+T cells and myeloid components develop normally. This indicates that expression in ancestral cells and CD4+CD8+thymocytes is not necessary. The antiviral activity of...
2023-09-12
Reproduction method: Adult rats were raised in a single cage and given a sufficient amount of medicated feed (rhubarb, mirabilite, and standard feed materials were evenly mixed in a ratio of 0.85:0.15:9.0 to make medicated feed, with 0.1g of raw medi...
2023-09-12
Gene knockout mice with B cell defects. In B cell deficient Igh-6 gene knockout mice, homozygotes lack mature B cells and cannot express membrane bound IgM. This mouse is mainly used to study the function of B cells in the immune system. For example,...
2023-09-12
Reproduction method: Adult rats were orally gavaged with Shanxi white vinegar at a dose of 10ml/kg body weight for 10 consecutive days. Observe changes in food intake, spontaneous activity, body weight, rectal temperature, stool characteristics, and ...
2023-09-12
The purpose of this study is to investigate whether the animal nasal aerosol exposure device can operate normally and generate aerosol particles with a specific particle size, and to explore the air tightness, distribution uniformity and disinfection...
2023-09-11
To preliminarily investigate the effect of intermittent hypoxic preconditioning on epileptic seizures in rats induced by lithium chloride and pilocarpine and its brain protective mechanism...
2023-09-11