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【Animal modeling】-The expression changes and effects of BDNF and its receptor TrkB in hypoxia-preconditioned mice

【Animal modeling】-The expression changes and effects of BDNF and its receptor TrkB in hypoxia-preconditioned mice

To explore the expression changes and effects of BDNF, TrkB receptor and BDNF/TrkB signaling pathway in acute hypoxia and hypoxia preconditioning mice, to further improve the molecular mechanism of hypoxia preconditioning neuroprotection, and to prov...

2023-08-11
【Animal modeling】-Tissue distribution of sialic acid receptors in dogs and susceptibility to H3N2 subtype canine influenza virus

【Animal modeling】-Tissue distribution of sialic acid receptors in dogs and susceptibility to H3N2 subtype canine influenza virus

To determine the type and distribution of influenza virus receptors in different tissues and organs of dogs, and to verify the susceptibility of dogs to H3N2 subtype canine influenza virus...

2023-08-11
【Animal Modeling】-Study on the safety and efficacy of human umbilical cord mesenchymal stem cells in the treatment of acute lung injury in mice

【Animal Modeling】-Study on the safety and efficacy of human umbilical cord mesenchymal stem cells in the treatment of acute lung injury in mice

To investigate the safety and efficacy of human umbilical cord mesenchymal stem cells (HUC-MSCs) in the treatment of lipopolysaccharide (LPS)-induced acute lung injury in mice...

2023-08-11
【Animal Modeling】-Establishment and evaluation of a rat model of mixed bacterial pneumonia

【Animal Modeling】-Establishment and evaluation of a rat model of mixed bacterial pneumonia

To establish a mixed bacterial infection pneumonia model of Staphylococcus aureus, Streptococcus pneumoniae and Escherichia coli, and provide animal model support for drug efficacy evaluation...

2023-08-04
[Animal modeling] - miR-214 protects neurons from damage after Propofol anesthesia in rats

[Animal modeling] - miR-214 protects neurons from damage after Propofol anesthesia in rats

To verify the delayed effect of Bevacizumab injection on wound healing of cynomolgus monkeys by observing the effect of Bevacizumab injection on the speed of wound healing of the back skin of cynomolgus monkeys and the expression of CD34 in the injur...

2023-08-03
【 Animal Modeling 】 - The Effect of Danggui Ginger Sheep Meat Decoction on Traditional Chinese Medicine Syndrome of IBS-D Rats with Spleen and Kidney Yang Deficiency Type

【 Animal Modeling 】 - The Effect of Danggui Ginger Sheep Meat Decoction on Traditional Chinese Medicine Syndrome of IBS-D Rats with Spleen and Kidney Yang Deficiency Type

To explore the traditional Chinese medicine syndrome manifestations of spleen and kidney yang deficiency model and observe the improvement effect of Danggui Shengjiang Yangrou Tang on traditional Chinese medicine syndrome in IBS-D female rats with sp...

2023-08-03
【Animal Modeling】-Relevant mechanism of hypertonic saline protecting blood-brain barrier and reducing cerebral edema in rats with cerebral hemorrhage

【Animal Modeling】-Relevant mechanism of hypertonic saline protecting blood-brain barrier and reducing cerebral edema in rats with cerebral hemorrhage

To investigate the related mechanism of hypertonic saline treatment in reducing cerebral edema in rats with cerebral hemorrhage...

2023-08-02
【Animal Modeling】-anatomical injury model

【Animal Modeling】-anatomical injury model

The theoretical basis of the anatomical injury model is the reentry theory of atrial flutter/atrial fibrillation, that is, the unidirectional circulation of one or more pulses in a closed loop...

2023-08-02
【Animal Modeling】-The changes of cytokines in the process of hepatocarcinogenesis in rats with oxymatrine combined with all-trans retinoic acid

【Animal Modeling】-The changes of cytokines in the process of hepatocarcinogenesis in rats with oxymatrine combined with all-trans retinoic acid

To observe the effect of oxymatrine combined with all-trans retinoic acid in inhibiting the formation of liver cancer in rats induced by diethylnitrosamine (DEN), and to explore its mechanism...

2023-08-02
【Animal model】-SLE rabbit model induced by allogeneic hepatic cytoplasmic protein

【Animal model】-SLE rabbit model induced by allogeneic hepatic cytoplasmic protein

Immune rabbits with allogeneic hepatocyte protein, and induce various autoantibodies, abnormal renal function and proteinuria. It is similar to the clinical manifestations of human SLE...

2023-08-02
【Animal Modeling】-Comparison of two different reagents for the four detection results of hemagglutination in SD rats

【Animal Modeling】-Comparison of two different reagents for the four detection results of hemagglutination in SD rats

To compare the four-item (PT, APTT, TT, FIB) detection results of hemagglutination reagents from two different manufacturers, imported and domestic, on experimental animals SD rats and humans, and to observe whether there is any difference between th...

2023-08-02
【Animal Modeling】-High-throughput sequencing to study the effects of drinking water with different pH on the intestinal microbes of SPF mice

【Animal Modeling】-High-throughput sequencing to study the effects of drinking water with different pH on the intestinal microbes of SPF mice

To study the effects of drinking water with different pH on gut microbial diversity in SPF mice...

2023-08-01
【Animal Experiment】-Establishment of Morphine Dependence Rat Model

【Animal Experiment】-Establishment of Morphine Dependence Rat Model

Purpose   (1) Familiar with the method of establishing morphine-dependent rat model, and copy the morphine-dependent rat model.    (2) Observe and score the withdrawal symptoms of morphine-dependent rats to determine whether a morphine-dependen...

2023-08-01
【Animal modeling】-Immune protection of Sap2 protein and dendritic cells against systemic Candida albicans infection

【Animal modeling】-Immune protection of Sap2 protein and dendritic cells against systemic Candida albicans infection

Mice were immunized with recombinant protein and dendritic cells (DC) to observe the immune protection effect on systemic Candida albicans...

2023-07-31
【Animal Modeling】-Establishment and Evaluation of Rat Vaginitis Model

【Animal Modeling】-Establishment and Evaluation of Rat Vaginitis Model

To establish a rat model of vaginitis, and to provide a new model for the development and evaluation of vaginitis treatment drugs...

2023-07-31
【Animal Modeling】-improved New Zealand Rabbit Common Carotid Artery Cannulation Fixation Method

【Animal Modeling】-improved New Zealand Rabbit Common Carotid Artery Cannulation Fixation Method

To investigate a stable, not easy to fall off, and continuous and timed blood collection method for the common carotid artery cannulation of New Zealand rabbits...

2023-07-31