[Animal modeling] - Establishment of mouse model of intrauterine adhesions by cervical mechanical injury combined with lipopolysaccharide perfusion

To establish an animal model of intrauterine adhesions according to the characteristics of clinical injury by using mechanical injury combined with lipopolysaccharide perfusion in a minimally invasive manner, so as to provide support for the in-depth...

2022-10-19

[Animal modeling] - Study on the conditions of modeling Parkinson\'s disease in rats with protease inhibitor

To observe the effects of different doses of protease inhibitor on behavior and tyrosine hydroxylase α- To explore the best condition of chronic model of Parkinson\'s disease induced by PSI...

2022-10-19

[Animal modeling] - Construction and evaluation of a mouse model of chronic cardiac toxicity induced by doxorubicin

To evaluate the effects of doxorubicin in different concentrations on cardiac toxicity in mice based on pathological changes...

2022-10-19

[Animal modeling] - Overexpression of LAMP2A in substantia nigra improves motor function of Parkinson\'s disease rhesus monkey model

To observe the effect of over expression of lysosome associated membrane protein 2A in substantia nigra on motor behavior of experimental monkeys induced by chaperone mediated autophagy in a Parkinson\'s disease rhesus monkey model...

2022-10-19

[Animal modeling] Study on the effect of Siwu Mixture on primary dysmenorrhea model mice induced by oxytocin

To study the effect of Siwu mixture on primary dysmenorrhea in mice and its possible mechanism...

2022-10-19

[Animal modeling] - Effect of human umbilical cord mesenchymal stem cells on autophagy level in hippocampus of naturally aging rats

To investigate whether transplantation of human umbilical cord mesenchymal stem cells can improve learning and memory and cognitive decline by regulating autophagy level in naturally aging rats...

2022-10-19

[Animal modeling] - Study on the protective effect and mechanism of estrogen on oxidative stress injury of mouse osteoblast MC3T3-E1

To investigate the protective effect and mechanism of estrogen on oxidative stress injury of mouse osteoblast MC3T3-E1...

2022-10-19

[Animal modeling] - Lipid lowering effect of citrus polymethoxy flavone biscuit on hyperlipidemia mice

This study is the first to evaluate the lipid-lowering effect of adding citrus polymethoxyflavone powder to biscuits in hyperlipidemia mouse model through the measurement of lipid metabolism experimental indicators, in order to provide a basis for de...

2022-10-19

【Animal modeling】-Optimization of dose-response relationship between N-ethyl-N-nitrosourea and cyclophosphamide in pig-a gene mutation test in rats

To study the effect of different doses of N-ethyl-N-nitrosourea (ENU) and cyclophosphamide (CP) on the deletion rate of ankyrin CD59 in peripheral blood red blood cells of SD rats, and to optimize the Pig-a gene mutation test Detection method...

2022-10-19

【Animal modeling】-Inhibitory effect of atrial natriuretic peptide on the growth of transplanted melanoma in knockout mice

To investigate the effect of atrial natriuretic peptide on the growth of melanoma...

2022-10-19

[Animal modeling] Effect of deletion of ubiquitin carboxyl terminal hydrolase 1 gene on reproductive system development of female mice

To study the effect of ubiquitin carboxyl terminal hydrolase L1 gene deletion on the reproductive system of female mice...

2022-10-18

[Animal modeling] - Study on the promoting effect and mechanism of cord blood mononuclear cells on angiogenesis in rats with acute myocardial infarction

To investigate the effect and mechanism of cord blood mononuclear cells (HCMNCs) on angiogenesis in rats with acute myocardial infarction (AMI)...

2022-10-18

[Animal modeling] - Effect of electroacupuncture on synaptic plasticity and microglial cell polarization in rats with cerebral ischemia

To investigate the effects of electroacupuncture on synaptic plasticity and microglial polarization in rats with focal cerebral ischemia, and to detect the expression of miR-21/signal transducer and activator of transcription 3 (STAT3) pathway...

2022-10-18

[Animal modeling] - Based on the rat OVX model, study the effect of estrogen deficiency on the degeneration of endplate chondrocytes

To investigate the effect of estrogen deficiency on the degeneration of endplate chondrocytes...

2022-10-18

[Animal modeling] - The effect of compound rehmannia granules on the regulation of serum cyclic nucleotides and the repair of dopaminergic neurons in Parkinson\'s disease mice with yin deficiency and

To explore the effect of Fufang Dihuang Granules on the regulation of serum cyclic nucleotides (cAMP, cGMP) and the repair of dopaminergic neurons in Parkinson\'s disease mice with yin deficiency and movement wind syndrome...

2022-10-18

【Animal Modeling】-Analysis of Right Heart Function in Rats with Alkaline Pulmonary Hypertension

To study the relationship between the evolution of pulmonary artery pressure and the evolution of right ventricular function...

2022-10-17