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【Animal modeling】-Effect of rapamycin on proliferation of rat aortic valve interstitial cells

【Animal modeling】-Effect of rapamycin on proliferation of rat aortic valve interstitial cells

To use rapamycin to target mTOR and investigate its effect on the proliferation of rat heart valve interstitial cells...

2023-02-02
【Animal Modeling】- Rat Mycoplasma Pneumoniae Model

【Animal Modeling】- Rat Mycoplasma Pneumoniae Model

Replication method Inoculate the international standard Mycoplasma pneumoniae FH strain (ATCC15531) into the mycoplasma liquid medium (the main components are bovine brain heart injection, sterile fetal bovine serum, fresh yeast injection, glucose, p...

2023-02-02
【Animal Modeling】-The effect of exercise on pancreatic islets in diabetic rats and its mechanism

【Animal Modeling】-The effect of exercise on pancreatic islets in diabetic rats and its mechanism

To investigate the effect of aerobic exercise on pancreatic islets and β cells in type 2 diabetic rats and its mechanism...

2023-02-02
【Animal Modeling】-Study on the polymorphisms of SLA class Ⅱ genes in SPF large white pigs and Landrace pigs

【Animal Modeling】-Study on the polymorphisms of SLA class Ⅱ genes in SPF large white pigs and Landrace pigs

Based on 3.0 T magnetic resonance imaging (MRI) technology, to observe the morphology and anatomy of WHBE rabbit brain in vivo, and to accumulate basic biological data of imaging of WHBE rabbit brain, so as to provide background information for furth...

2023-02-01
【Animal Modeling】-Preliminary study on the location of microinjection in the nucleus tractus solitarius in rats

【Animal Modeling】-Preliminary study on the location of microinjection in the nucleus tractus solitarius in rats

Through the application of different parameters for positioning injection, explore the positioning method of the nucleus tractus solitarius microinjection to improve the injection success rate and accuracy...

2023-02-01
Research reveals the new member of early angiosperms-change fruit

Research reveals the new member of early angiosperms-change fruit

The origin and early evolution of angiosperms have been a problem that botanists have been trying to overcome for a long time. The way to solve this problem is to find fossil evidence...

2023-01-31
【Animal Modeling】-Study on the alleviation of exercise via FoxO1-lipophagy pathway. Study on hyperlipidemia in ApoE-/- mice

【Animal Modeling】-Study on the alleviation of exercise via FoxO1-lipophagy pathway. Study on hyperlipidemia in ApoE-/- mice

Lipophagy is a selective autophagy targeting fat and is regulated by FoxO1. As an effective means of regulating lipid metabolism disorders, there is no report on whether exercise is related to FoxO1-lipophagy process in hyperlipidemia....

2023-01-31
【Animal Modeling】-Animal model of stress gastric ulcer induced by hot water scald

【Animal Modeling】-Animal model of stress gastric ulcer induced by hot water scald

Feeding method Anesthetized adult experimental rats with 30 mg/kg body weight of pentobarbital sodium injected intraperitoneally without ascites after fasting for 24 hours are placed in a hot water bath at 80-92°C for 10-18 seconds...

2023-01-31
【Animal Modeling】-Prophylactic administration of all-trans retinoic acid can relieve rheumatoid arthritis model

【Animal Modeling】-Prophylactic administration of all-trans retinoic acid can relieve rheumatoid arthritis model

Explore the effects of all-trans retinoic acid (ATRA) on type II collagen (CII)-induced rheumatoid arthritis (CIA) rat arthritis formation stage joint tissue structure, serum expression of related inflammatory cytokines, and cartilage damage Influenc...

2023-01-31
【Animal Modeling】-How to establish a nude mouse myeloid leukemia model?

【Animal Modeling】-How to establish a nude mouse myeloid leukemia model?

Use BALB/c nude mice to establish M1 leukemia model?...

2023-01-30
【Animal Modeling】-Ovalbumin (OVA) sensitization combined with smoking method to establish cough variant asthma guinea pig model

【Animal Modeling】-Ovalbumin (OVA) sensitization combined with smoking method to establish cough variant asthma guinea pig model

Try to use ovalbumin in combination with smoking to establish a more similar guinea pig CVA model...

2023-01-30
【Animal modeling】-Effect of baicalin on experimental autoimmune encephalomyelitis mice

【Animal modeling】-Effect of baicalin on experimental autoimmune encephalomyelitis mice

To observe the effect of different concentrations of baicalin (baicalin) on experimental autoimmune encephalomyelitis mouse model, and to study its preliminary mechanism...

2023-01-30
【Animal Modeling】-The regulatory mechanism of peripheral pain sensation in rats based on the interaction of TRPV1 and P2X3

【Animal Modeling】-The regulatory mechanism of peripheral pain sensation in rats based on the interaction of TRPV1 and P2X3

To observe the relationship between peripheral TRPV1 and P2X3 in rats, in order to partially elucidate the regulatory mechanism of peripheral pain sensation...

2023-01-29
[Animal modeling] - Study on the anti-colon cancer effect of five species of Ferula in Xinjiang based on cell and animal experiments

[Animal modeling] - Study on the anti-colon cancer effect of five species of Ferula in Xinjiang based on cell and animal experiments

To study the effects of five kinds of ferula from Xinjiang and their different polar parts on the proliferation inhibition and apoptosis of human colon cancer HCT 116 cells in vitro, and to study the effects of five kinds of ferula from Xinjiang on c...

2023-01-29
[Animal modeling] - protective effect of miR-214 on postoperative neuronal damage in rats anesthetized with propofol

[Animal modeling] - protective effect of miR-214 on postoperative neuronal damage in rats anesthetized with propofol

To explore the effect of cannabinol on monoamine neurotransmitters in the central nervous system in methamphetamine dependent rats, explain the therapeutic mechanism of CBD on METH dependence, and provide reference for the development of drug depende...

2023-01-29
[Animal modeling] - Kaixinsan injected A into bilateral hippocampal CA1 area β Study on the therapeutic effect and mechanism of AD rats induced by 1-42

[Animal modeling] - Kaixinsan injected A into bilateral hippocampal CA1 area β Study on the therapeutic effect and mechanism of AD rats induced by 1-42

To investigate the effect of Kaixinsan on the injection of A into bilateral hippocampal CA1 region β The therapeutic effect of 1-42 on AD rats, and its mechanism of action is preliminarily clarified...

2023-01-29