
To establish a related mouse knee osteoarthritis model by knocking out SIRT1 gene, and to observe the differences in the morphology of cartilage tissue sections with different single staining or compound staining techniques...
2023-01-29
Osteoporosis model constructed with ovariectomized rats is the most suitable model to study postmenopausal osteoporotic disease, however, the effect on skin after ovary removal in rats is seldom studied....
2023-01-29
A few days ago, the Institute of Neuroscience of Soochow University and Professor Hua Yimin of Cold Spring Harbor Laboratory in the United States developed a number of mouse disease models, which effectively increased the expression of motor neuron s...
2023-01-18![[Animal modeling]-Infectious SIV exists in the fatty tissue of chronically infected rhesus monkeys and causes metabolic defects](/./uploads/images/default/default.png)
Memory CD4 T cells and macrophages are the main host and cell bank of humans and HIV in non-human primates...
2023-01-18
To investigate the effect of hydrogen-rich solution on the apoptosis of hippocampal neurons and the expression of PI3K/Akt/FoxO1 signaling pathway induced by cerebral ischemia-reperfusion in rats...
2023-01-18
How to evaluate the effects of aerobic exercise and metformin combined with aerobic exercise on vascular oxidative stress in type 2 diabetic rats?...
2023-01-18
How to establish an effective method for genotyping Leprdb/+ mouse offspring using TaqMan probe fluorescence quantitative PCR technology...
2023-01-18
To study effective methods to avoid darkness and Morris water maze experiment to establish a model of learning and memory impairment in mice...
2023-01-18
MIT researchers showed in mice that a gene editing system called CRISPR can be used to generate colon tumors that are very similar to human tumors...
2023-01-18
反复脑缺血再灌法建立学习记忆障碍模型...
2023-01-18![[Animal modeling]-Different concentrations of Aβ25-35 protein to simulate Alzheimer\\\\](/./uploads/images/default/default.png)
After intracerebroventricular injection of different concentrations of amyloid Aβ25-35, observe the changes in the learning and memory ability of the Morris water maze in rats, determine the optimal concentration of Aβ25-35 injection for AD model rat...
2023-01-18
To explore electroacupuncture on synaptic plasticity and microglia polarization in rats with focal cerebral ischemia, and to detect the expression of miR-21/signal transducer and activator of transcription 3 (STAT3) pathway...
2023-01-17
To explore the application of intravascular shunt plug in establishing heterotopic abdominal heart transplantation rat model...
2023-01-17
To use 16S rRNA high-throughput sequencing method to determine the oral flora of several commonly used experimental animals (Tibetan miniature pigs, beagle dogs, macaques, New Zealand rabbits, Wistar rats), and to compare and analyze the oral flora o...
2023-01-17![[Animal Modeling]-Based on SDF-1/CXCR4 signal pathway to explore the effect of Xin\\](/./uploads/images/default/default.png)
Objective Based on the SDF-1/CXCR4 signaling pathway, to explore the effect of Xin\\\'an Biyuan Prescription on the apoptosis of olfactory epithelial neurons in rats with acute sinusitis...
2023-01-17
To study the effects of PM2.5 on reproductive endocrine hormone levels and pregnancy outcomes in female rats...
2023-01-17