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【Animal Modeling】-Review on Experimental Animal Models of Alzheimer\'s Disease

【Animal Modeling】-Review on Experimental Animal Models of Alzheimer\'s Disease

Alzheimer\'s disease is an age-related irreversible neurodegenerative disease of unknown etiology. The clinical manifestations are mainly cognitive and memory loss...

2022-09-05
【Animal modeling】-Methods and comparison of orthotopic mouse pancreatic cancer model suitable for minimally invasive ablation research

【Animal modeling】-Methods and comparison of orthotopic mouse pancreatic cancer model suitable for minimally invasive ablation research

To explore the advantages and disadvantages of using tumor cell orthotopic injection and tumor tissue block transplantation to establish a mouse pancreatic cancer orthotopic model, and to provide technical reference for the establishment of a mouse p...

2022-09-05
【Animal modeling】-Construction and evaluation of doxorubicin-induced chronic cardiotoxicity model in mice

【Animal modeling】-Construction and evaluation of doxorubicin-induced chronic cardiotoxicity model in mice

To evaluate the modeling effect of different concentrations of doxorubicin-induced cardiotoxicity model in mice based on pathological changes...

2022-09-05
【Animal Modeling】-Establishment of endothelial cell conditional knockout EMCN mouse model and comparative analysis of tumor lung metastasis

【Animal Modeling】-Establishment of endothelial cell conditional knockout EMCN mouse model and comparative analysis of tumor lung metastasis

To establish a mouse model of endothelial cell conditional knockout of EMCN gene, and to explore the differences in lung metastasis between C57BL/6 mice and endothelial cells conditional knockout of EMCN mouse model...

2022-09-05
【Animal modeling】-Establishment of LCMV-CL13 chronic infection mouse model and analysis of BCR mutation

【Animal modeling】-Establishment of LCMV-CL13 chronic infection mouse model and analysis of BCR mutation

To establish a mouse model of chronic lymphocytic choriomeningitis virus LCMV-CL13 infection, and to analyze its possibility as a model for high-frequency mutation of B cell receptors...

2022-09-05
【Animal modeling】-Study on biological characteristics of H1N1 influenza virus tree shrew model

【Animal modeling】-Study on biological characteristics of H1N1 influenza virus tree shrew model

To establish a tree shrew model of H1N1 influenza virus infection, and to explore the dynamics of influenza virus and its distribution in respiratory tissues...

2022-09-05
【Animal modeling】-Arachidonic acid-induced establishment of diffuse cerebral thrombosis model in rats

【Animal modeling】-Arachidonic acid-induced establishment of diffuse cerebral thrombosis model in rats

To establish and optimize the rat model of diffuse cerebral thrombosis induced by arachidonic acid...

2022-09-05
【Animal Modeling】-Comparative Study on Visceral Hypersensitivity Models Induced by Combined Method

【Animal Modeling】-Comparative Study on Visceral Hypersensitivity Models Induced by Combined Method

To observe the effect of maternal-infant separation combined with mechanical stimulation and drug combined with chronic stress on the visceral hypersensitivity model of irritable bowel syndrome, and to explore the advantages and disadvantages of the ...

2022-09-05
【Animal Modeling】-Comparative Study on the Rat Model of Chronic Skin Ulcer

【Animal Modeling】-Comparative Study on the Rat Model of Chronic Skin Ulcer

To construct a rat model of chronic skin ulcer by different methods, and to evaluate the differences and respective characteristics of different models through a variety of indicators...

2022-09-05
【Animal modeling】-Construction of mouse intrauterine adhesion model by transcervical mechanical injury combined with lipopolysaccharide perfusion

【Animal modeling】-Construction of mouse intrauterine adhesion model by transcervical mechanical injury combined with lipopolysaccharide perfusion

  Objective To construct an animal model of intrauterine adhesions that conforms to clinical injury characteristics by a minimally invasive method using mechanical injury combined with lipopolysaccharide perfusion, so as to provide support for in-dep...

2022-09-05
【Animal modeling】-Protease inhibitor on the conditions of rat Parkinson\'s disease modeling

【Animal modeling】-Protease inhibitor on the conditions of rat Parkinson\'s disease modeling

To observe the effects of different doses of protease inhibitors on rat behavior and the expression of tyrosine hydroxylase and α-synuclein in the substantia nigra, and to explore the optimal conditions for a chronic model of PSI-induced Parkinson\'s...

2022-09-05
【Animal Modeling】-3D Reconstruction and Vascular 3D Printing Model of Miniature Pig Lungs

【Animal Modeling】-3D Reconstruction and Vascular 3D Printing Model of Miniature Pig Lungs

To explore the method of establishing 3D reconstruction model of minipig lung and the application of 3D printing model...

2022-09-05
【Animal modeling】-Construction and evaluation of doxorubicin-induced chronic cardiotoxicity model in mice

【Animal modeling】-Construction and evaluation of doxorubicin-induced chronic cardiotoxicity model in mice

To evaluate the modeling effect of different concentrations of doxorubicin-induced cardiotoxicity model in mice based on pathological changes...

2022-09-05
【Animal Modeling】- Overexpression of LAMP2A in the substantia nigra improves motor function in a rhesus monkey model of Parkinson\'s disease

【Animal Modeling】- Overexpression of LAMP2A in the substantia nigra improves motor function in a rhesus monkey model of Parkinson\'s disease

To observe the effect of substantia nigra overexpressing lysosome-associated membrane protein 2A up-regulating molecular chaperone-mediated autophagy on the motor behavior of experimental monkeys in a rhesus monkey model of Parkinson\'s disease...

2022-09-05
【Animal Modeling】-Establishment and evaluation of an animal model of Alzheimer\'s disease-phlegm-stasis syndrome combination

【Animal Modeling】-Establishment and evaluation of an animal model of Alzheimer\'s disease-phlegm-stasis syndrome combination

The purpose of this study is to explore the establishment of a reliable disease-syndrome combination animal model of Alzheimer\'s disease and phlegm-stasis syndrome, to provide a corresponding animal model for the prevention and treatment of AD with ...

2022-09-05
【Animal Modeling】-High-fat and high-sugar diet-induced changes in intestinal flora in Wuzhishan miniature pig atherosclerosis model

【Animal Modeling】-High-fat and high-sugar diet-induced changes in intestinal flora in Wuzhishan miniature pig atherosclerosis model

To observe the changes of intestinal flora in Wuzhishan miniature pig atherosclerosis model induced by high-fat and high-sugar diet...

2022-09-05